
Chemistry Letters p. 73 - 74 (1999)
Update date:2022-08-05
Topics:
Ueoka, Ryuichi
Goto, Kouichi
Tanoue, Osamu
Miki, Atsushi
Yoshimitsu, Shinya
Imamura, Chikara
Ihara, Yasuji
Murakami, Yukito
The diastereoselectivity for the hydrolysis of p-methoxycarbonylphenyl N-(benzyloxycarbonyl)-D(L)-phenylalanyl-L-leucinate in aqueous solution was inverted by changing concentrations of the substrates or the reaction temperature. The monomer-aggregate transition operated on the LL-substrate, which was suggested by the spectroscopic measurements, seems to be responsible for such behavior.
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