Synthesis of natural PI(3,4,5)P3

DOI: 10.1016/S0040-4039(98)00034-3

Source and publish data:

Tetrahedron Letters p. 1583 - 1586 (1998)

Update date:2022-07-30

Topics:

Authors:

Watanabe, Yutaka

Nakatomi, Mitsunobu

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Article abstract of DOI:10.1016/S0040-4039(98)00034-3

Natural phosphatidylinositol 3,4,5-trisphosphate which has been believed to have stearoyl and arachidonoyl groups at the sn-1 and -2 positions, respectively, has been synthesized using 1,2-O-cyclohexylidene 3,4-O-disiloxanyl-myo-inositol as the pivotal intermediate.

Full text of DOI:10.1016/S0040-4039(98)00034-3

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Product name:1D-6-O-<(S)-(+)-O-acetylmandeloyl>-1,2-O-cyclohexylidene-3,4-O-(tetraisopropyldisiloxane-1,3-diyl)-5-O-triethylsilyl-myo-inositol

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