Oxiranes with quinolone substitution: Stereoselective synthesis and antiviral activity

DOI: 10.1016/0960-894X(96)00125-4

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 871 - 874 (1996)

Update date:2022-08-17

Topics:

Authors:

Kidwai Kidwai

Kumar Kumar

Goel Goel

Srivastava

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Article abstract of DOI:10.1016/0960-894X(96)00125-4

A series of new quinoline substituted oxiranes were synthesized by the reaction of 2-N-(chloroacetyl)-1-(4'-methyl-2'-quinolinyl) hydrazine and aromatic aldehydes. These compounds were tested against encephalomyocarditis virus (EMVC) and only two compounds exhibited protection against the virus.

Full text of DOI:10.1016/0960-894X(96)00125-4

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