Synthesis of (3S,4S)-4-Hydroxy-2,3,4,5-Tetrahydropyridazine-3-Carboxylic Acid, Component of Luzopeptin A.

DOI: 10.1016/0957-4166(95)00258-Q

Source and publish data:

Tetrahedron Asymmetry p. 1989 - 1994 (1995)

Update date:2022-08-16

Topics:

Authors:

Greck, Christine

Bischoff, Laurent

Genet, Jean Pierre

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0957-4166(95)00258-Q

The enantioselective synthesis of (3S,4S)-4-hydroxy-2,3,4,5-tetrahydropyridazine-3-carboxylic acid 1 is described.The two stereogenic centers in anti relationship are obtained by sequential enantio and chemoselective hydrogenation of β-ketoester in presence of chiral ruthenium catalyst and diastereoselective amination of β-hydroxyester with di t-butylazodicarboxylate.

Full text of DOI:10.1016/0957-4166(95)00258-Q

Products guided by the article

Product name:3-Pyridazinecarboxylicacid,2,3,4,5-tetrahydro-4-hydroxy-,methylester,(3R,4R)-(9CI)

Cas No:217447-50-2

R&D Labs maybe for 217447-50-2

Suzhou Ryan Pharmachem Technology Co.,Ltd

Contact:+86-0512-68780025

Address:B-301,No.2 Taishan Road,Suzhou New District,Jiangsu,P.R. China
Shanghai Massive Chemical Technology Co., Ltd.

website:http://www.massivechem.com/

Contact:+86 21 34943721

Address:Room 435, 4th floor, Building 9, No. 2568 Gudai Road,Minhang District, Shanghai,
Huayi Isotopes Co.

Contact:+ 86 512 52491118

Address:1 Fuyu Road, Haiyu TownChangshu, Jiangsu, China
Chongqing Shuangfeng Chemical Co.,Ltd

Contact:+86-23-49850156

Address:No.663,xuanhua Rd,yongchuan,chongqing,China
Sdow

website:http://www.sdowchem.com

Contact:86-135-2193 7483

Address:8-106 taiyue building

Relevant to this article

Mo-catalyzed deoxygenation of epoxides to alkenes

Doi:10.1016/j.mcat.2017.03.020
(2017)
A powerful tool for acid catalyzed organic addition and substitution reactions

Doi:10.1039/c4ra17321j
(2015)
THE ABSOLUTE CONFIGURATIONS OF (+)-THALICTRIFOLINE AND (+)-CORYDALIC ACID METHYL ESTER. TOTAL SYNTHESIS OF (+)-THALICTRIFOLINE.

Doi:10.1016/S0040-4039(01)82899-9
(1981)
Thermal, four-carbon + three-carbon cycloaddition reaction of cyclopropenone ketals. Total synthesis of deacetamidocolchiceine: Formal total synthesis of colchicine

Doi:10.1021/jo00218a042
(1985)
Polymethylhydrosiloxane reduction of carbonyl function catalysed by titanium tetrachloride

Doi:10.4314/bcse.v32i1.18
(2018)
Syntheses and structures of a class of bridged bis(amidinate)s and derivatives

Doi:10.3184/174751918X15260497205682
(2018)

Article Doi