An efficient chemo-enzymatic synthesis of α-amino-β-hydroxy-γ butyrolactone

DOI: 10.1016/0040-4039(95)00924-2

Source and publish data:

Tetrahedron Letters p. 5063 - 5064 (1995)

Update date:2022-08-10

Topics:

Authors:

Vassilev, Vassil P.

Uchiyama, Taketo

Kajimoto, Tetsuya

Wong, Chi-Huey

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Article abstract of DOI:10.1016/0040-4039(95)00924-2

The synthesis of (25,3R)-2-amino-3-hydroxybutyrolactone, a precursor of the monobactam antibiotic Carunoman, has been accomplished in three steps involving the use of L-threonine aldolase.

Full text of DOI:10.1016/0040-4039(95)00924-2

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