Curtius degradation in solid-phase synthesis

DOI: 10.1016/S0040-4039(98)01941-8

Source and publish data:

Tetrahedron Letters p. 8747 - 8750 (1998)

Update date:2022-08-16

Topics:

Authors:

Richter, Lutz S.

Andersen, Stina

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Article abstract of DOI:10.1016/S0040-4039(98)01941-8

An optimized and broadly applicable procedure for the solid-phase synthesis of primary amines and carbamates via Curtius-degradation of carboxylic acids has been developed. The targeted primary amines and carbamates were obtained in excellent purity and high overall yields.

Full text of DOI:10.1016/S0040-4039(98)01941-8

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