
Tetrahedron Letters p. 9385 - 9388 (1998)
Update date:2022-08-16
Topics:
Robustell, Brian J.
Abe, Ikuro
Prestwicht, Glenn D.
A convergent asymmetric synthesis led to (3S)-14-fluoro-2,3- oxidosqualene (14-FOS, 16), which was cyclized by bacterial squalene:hopane cyclase to a monocarbocyclic product with a bridged ether and a 2:3 mixture of bicyclic alcohols. 14-FOS was neither a
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