A novel tautomerism in alkyl dihydropyrimidines: Observation of tautomerism by H-D exchange of 2- and/or 4-methyl protons of dihydropyrimidines in CD3OD

Article abstract of DOI:10.1016/S0040-4039(00)78907-6

A novel tautomerism was found in dihydropyrimidines such as 2-amino-4,6,6-trimethyldihydropyrimidine 1 and 2,4,6,6-tetramethyldihydropyrimidine 2 by the observation of H-D exchange on both 4-methyl protons of 1 and 2,4-dimethyl protons of 2 by the treatme