
Tetrahedron Asymmetry p. 2497 - 2500 (1997)
Update date:2022-08-17
Topics:
Lopez, Francisco J.
Ferrino, Sergio A.
Reyes, Mario S.
Roman, Ruth
Several chiral derivatives of racemic naproxen were subjected to asymmetric transformations. Notably, asymmetric transformation of the second kind of a mixture of 2b and 3b gave a diastereomeric excess (d.e.) over 90% in favor of 2b. This d.e. was increased to over 99% after recrystallization.
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