Motuporin, a potent protein phosphatase inhibitor isolated from the Papua New Guinea sponge Theonella swinhoei gray

DOI: 10.1016/S0040-4039(00)91674-5

Source and publish data:

Tetrahedron Letters p. 1561 - 1564 (1992)

Update date:2022-08-11

Topics:

Authors:

De Silva

Williams

Andersen

Klix Klix

Holmes Holmes

Allen Allen

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Article abstract of DOI:10.1016/S0040-4039(00)91674-5

Motuporin (1), a cyclic pentapeptide that is a potent protein phosphatase-1 inhibitor and cytotoxin, has been isolated from the marine sponge Theonella swinhoei collected in Papua New Guinea. The structure of motuporin was elucidated by spectroscopic analysis and chemical degradation.

Full text of DOI:10.1016/S0040-4039(00)91674-5

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