Catalytic asymmetric dihydroxylation of alkenes using silica gel supported cinchona alkaloid

Article abstract of DOI:10.1016/0957-4166(96)00367-9

Immobilization of 3,6-bis(9-O-dihydroquinyl)pyridazine and 3,6-bis(9-O-dihydroquinidyl) pyridazine on silica gel support has been reported. The use of immobilized auxiliary has lead to comparable rate with that of the homogeneous catalytic AD of alkenes, however with lower ee.