A practical preparation of 4,4-diphenylcyclohexanol: A key intermediate in the synthesis of MS-325

Article abstract of DOI:10.1080/00397919808004943

A preparation of 4,4-diphenylcyclohexanol 2 is described from benzoin in five synthetic steps. The process uses readily available reagents and is suitable for manufacturing.

Full text of DOI:10.1080/00397919808004943

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Synthetic Communications:
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Synthetic Organic Chemistry
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A Practical Preparation of
4,4-Diphenylcyclohexanol:
A Key Intermediate in the
Synthesis of Ms-325
John C.Amedio Jr a , Paul J. Bernard a , Mark
Fountain a & Gerritt VanWagenen Jr. a
a Chemical Development , EPIX Medical, Inc. , 71
Rogers St, Cambridge, MA, 02142-1118, USA
Published online: 23 Aug 2006.
To cite this article: John C.Amedio Jr , Paul J. Bernard , Mark Fountain & Gerritt
VanWagenen Jr. (1998) A Practical Preparation of 4,4-Diphenylcyclohexanol:
A Key Intermediate in the Synthesis of Ms-325, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry,
28:20, 3895-3906, DOI: 10.1080/00397919808004943
To link to this article: http://dx.doi.org/10.1080/00397919808004943
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Evaluation Only. Created with Aspose.PDF. Copyright 2002-2021 Aspose Pty Ltd.

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