Chiral recognition of amino acid derivatives by 1,1′-binaphthalene-8,8′-diol

Article abstract of DOI:10.1016/0040-4039(96)00702-2

Optically active 1,1′-binaphthalene-8,8′-diol is found to bind a variety of amines in CDCl₃ or C₆D₆ solution. Significant chiral recognition (ΔΔG^o = ～1.2 kcal/mol) was observed in the valine derivative 4. A three-point binding motif is assumed. Copyright