A new two step route to 1-hydroxy-9H-3-carbazolecarboxylic acid derivatives from 3-formylindole. Application to the synthesis of mukonine

DOI: 10.1016/S0040-4020(97)10366-0

Source and publish data:

Tetrahedron p. 1585 - 1588 (1998)

Update date:2022-08-29

Topics:

Authors:

Brenna, Elisabetta

Fuganti, Claudio

Serra, Stefano

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Article abstract of DOI:10.1016/S0040-4020(97)10366-0

Carbazole alkaloid mukonine 6b was prepared from 3-formylindole in three steps (32% overall yield). The key step was the base-promoted cyclization of a mixed anhydride of mono ester mono acid 5.

Full text of DOI:10.1016/S0040-4020(97)10366-0

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Product name:1-Methoxy-9H-carbazole-3-carboxylic acid methyl ester

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