An Efficient Synthesis of the Antifungal Dilactone LL-Z1271α and of other Biologically Active Compounds

Article abstract of DOI:10.1016/00404-0399(50)0949D-

The syntheses of the terpenoid antifungal LL-Z1271α and other related compounds were achieved starting from the communic acids.The synthetic approach includes a mercuriation-demercuriation reaction of a γ,δ-unsaturated methyl ester in the presence of O2, giving rise to a lactone ring.