Helvetica Chimica Acta p. 1742 - 1748 (1991)
Update date:2022-08-29
Topics:
Kazimierczuk, Zygmunt
Mertens, Ralf
Kawczynski, Wieslaw
Seela, Frank
The synthesis of 2'-deoxyisoguanosine (2), and the pyrrolo<2,3-d>pyrimidine and pyrazolo<3,4-d>pyrimidine 2'-deoxyribonucleosides 3 and 4 is described.Condensation of the imidazole precursor 5 with benzoyl isocyanate followed by reaction with ammonia gave 2.Its N(7) regioisomer was obtained from 6.Compound 2 was also prepared by the photochemically induced conversion of 2-chloro- and 2-bromopurine 2'-deoxyribofuranosides 9a and 10, respectively, in aqueous solution.The photo reaction was further used for the synthesis of the compounds 3 and 4 starting with the amino-chloro-2'-deoxynucleosides 9b and 9c, respectively.
View MoreNantong Auxin Electronic Technology Co., LTD
Contact:86-513-88760026
Address:NO.5-1, Aoxin Road, Haian Hi-tech Development Zone, Jiangsu Province, China
Puyang Willing Chemicals Co.,Ltd.
Contact:86-393-4840366
Address:Puyang Henan China
Contact:86-371-63655023
Address:No.85,jinshui road,zhengzhou,China
Shanghai agrotree chemical co.,ltd.
Contact:+86-21-50117563
Address:Room 8A,liangfeng building,No.8 dongfang RD.pudong,shanghai,China
Shanghai better-in Medical Technology Co.,LTD.
Contact:+86-21-38921049
Address:Lane 720 zhangjianggaoke cailun road, Pudong, Shanghai, room 513
Doi:10.1007/BF02465833
(1998)Doi:10.1007/s10973-009-0280-4
(2009)Doi:10.1007/BF01946285
(1973)Doi:10.1016/S0040-4039(00)82333-3
(1988)Doi:10.1021/ja00452a037
(1977)Doi:10.1016/j.phytol.2009.12.002
(2010)