The effect of absorbing resins on substrate concentration and enantiomeric excess in yeast reduction

Article abstract of DOI:10.1016/S0957-4166(97)00257-7

The correlation between the enantiomeric excess (e.e.) of the (S)-(+)-ethyl-3-hydroxybutanoate 2, obtained in the baker's yeast reduction of ethyl acetoacetate 1, and the concentration of the substrates in the fermentation mixture has been studied by the use of two different techniques (absorbing resins and organic solvents) The presence of resins undoubtedly influences the enantiomeric excess of the product.