Phosphorus, Sulfur and Silicon and the Related Elements p. 1069 - 1074 (2016)
Update date:2022-08-11
Topics:
Bukharov, Sergey V.
Burilov, Alexander R.
Oludina, Yulia N.
Tagasheva, Roza G.
Syakaev, Viktor V.
Musin, Rashid Z.
Nugumanova, Gulnara N.
The synthesis of N-[dimethoxyphosphoryl-(3,5-di-tert-butyl-4-hydroxyphenyl)]methylisatins has been performed by the addition of isatin and 5-butylisatin to the double bond of dimethyl-(3,5-di-tert-butyl-4-oxo-2,5-cyclohexadienylidene)methylphosphonate. Subsequent functionalization of the compounds synthesized with thiosemicarbazide hydrochloride, 3-(3?,5?-di-tert-butyl-4?-hydroxyphenyl)propionic acid hydrazide, and isonicotinic acid. Hydrazide gave isatin derivatives containing several pharmacophore fragments. Each of them has the ability to the increase the antioxidant and biological activities of these compounds.
View MoreChengdu D-Innovation Pharmaceutical Co., Ltd
Contact:86-28-85105536
Address:1001, B6, No.88 Keyuan South Road, Chengdu Hi-Tech Zone
Guangzhou Flower's Song Fine Chemical CO,. Ltd
Contact:+86-20-87475199
Address:No.12, Fenghuang 3 Road, Jiulong Industrial Park, Luogang District, Guangzhou. China
Jiande City Silibase Silicone New Material Manufacture Co., Ltd.
Contact:15967177856
Address:Genglou Industrial Development Area
MS( MAOSHENG )Chemical CO.,LTD
Contact:+86-519-82726678.82726378
Address:TAOXI INDUSTRY ZONE JINTAN
Contact:+86 21 5017 5386
Address:No 999,Jiangyue Rd, Minhang Dist ,201114,Shanghai ,China
Doi:10.1021/jf000468l
(2000)Doi:10.1002/jhet.3976
(2020)Doi:10.1246/bcsj.20130015
(2013)Doi:10.1021/acs.inorgchem.7b01178
(2017)Doi:10.1016/j.tetlet.2008.04.129
(2008)Doi:10.1039/jr9370001114
(1937)