Synthesis of new alkylaminoalkyl thiosemicarbazones of 3-acetylindole and their effect on DNA synthesis and cell proliferation

DOI: 10.1016/0223-5234(96)88215-8

Source and publish data:

European Journal of Medicinal Chemistry p. 107 - 114 (1995)

Update date:2022-08-18

Topics:

Authors:

Siatra-Papastaikoudi

Tsotinis

Raptopoulou

Sambani Sambani

Thomou Thomou

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Article abstract of DOI:10.1016/0223-5234(96)88215-8

The preparation of a number of thiobemicarbazones of 3-acetylindole is described. These compounds were evaluated in vitro for their effect on proliferation and cell-division delays in cultured human peripheral blood lymphocytes, and their effect on DNA synthesit in T-cell leukemia Molt-4 cells.

Full text of DOI:10.1016/0223-5234(96)88215-8

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