Efficient synthesis of 2'-amino-2'-deoxypyrimidine 5'- triphosphates

Article abstract of DOI:10.1080/15257779508010694

The synthesis of 2'-amino-2'-deoxypyrimidine 5'-triphosphates is described. The 2'-amino-2'-deoxyuridine 5'-triphosphate is obtained from uridine in four steps with 25% overall yield. The 2'-amino-2'-deoxycytidine 5'-triphosphate is obtained from uridine in seven steps with 13% overall yield.

Full text of DOI:10.1080/15257779508010694

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Nucleosides and Nucleotides
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Efficient Synthesis of 2′-Amino-2′-
deoxypyrimidine 5′-Triphosphates
Danny P. C. McGee a , Chandra Vargeese a , Yansheng Zhai a ,
Gary P. Kirschenheuter a , Alecia Settle a , Colleen R. Siedem a &
Wolfgang A. Pieken a
a NeXagen Inc. , 2860 Wilderness Pl., Boulder, CO, 80301, USA
Published online: 24 Sep 2006.
To cite this article: Danny P. C. McGee , Chandra Vargeese , Yansheng Zhai , Gary P.
Kirschenheuter , Alecia Settle , Colleen R. Siedem & Wolfgang A. Pieken (1995) Efficient Synthesis
of 2′-Amino-2′-deoxypyrimidine 5′-Triphosphates, Nucleosides and Nucleotides, 14:6, 1329-1339,
DOI: 10.1080/15257779508010694
To link to this article: http://dx.doi.org/10.1080/15257779508010694
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