Archiv der Pharmazie p. 366 - 368 (2001)
Update date:2022-08-29
Topics:
Usifoh, Cyril O.
Some derivatives of 5,5-diphenylhydantoin (phenytoin) were synthesized by the alkylation of phenytoin with substituted methylene bromides. The hydantoins were evaluated for possible anticonvulsant activity in the maximal electroshock (MES)- and subcutaneous pentylenetetrazole (ScMet)-induced seizures and for neurotoxicity in the rotorod test in mice and rats.
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(2019)Doi:10.1021/acs.joc.8b02351
(2019)Doi:10.1016/j.ica.2018.08.021
(2018)Doi:10.1002/cctc.201601215
(2017)Doi:10.1016/0040-6031(87)80082-5
(1987)
