Preparation of 14C-labelled dimethylsilane-1,1-diol

Article abstract of DOI:10.1002/jlcr.2580340504

The preparation of ¹⁴C-labelled dimethylsilane-1,1-diol in two steps from ¹⁴C-labelled diphenyldimethylsilane is described. Aluminum chloride catalyzed protodesilylation of diphenyldimethyisilane with HCl in dichloromethane or dimethyldichlorosilane at 0-5°C affords labelled dimethyldichlorosilane which is hydrolyzed in the presence of triethylamine to afford the title compound in 45-60% yield.