MECHANISM OF THE REACTION OF 2-HALOKETONES WITH 2-AMINOPYRIDINE

Article abstract of DOI:10.1016/0040-4020(82)85044-8

Time-dependent 1H NMR spectra of DMSO-d6 solutions of p-substituted phenacyl bromides and 2-aminopyridine indicate that the formation of imidazo<1,2-a>pyridines occurs via two relatively long-lived intermediates, C and D, which are in equilibrium with eac