Journal of Organometallic Chemistry p. 265 - 267 (1996)
Update date:2022-08-11
Topics:
Slocum
Reed
Jackson III
Friesen
Rates and extents of directed ortho metalation (DoM) of anisole and p-methylanisole (p-MA) with n-BuLi have been measured in THF/n-hexane. About a 14% (v/v) solution of THF in the hydrocarbon provides an extent of metalation which exceeds that in neat THF
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