Chemistry Letters p. 1829 - 1832 (1983)
Update date:2022-08-11
Topics:
Tsuboi, Sadao
Masuda, Toshihide
Takeda, Akira
A stereoselective synthesis of (2E,4Z,7Z)-2,4,7-tridecatrienol, a key intermediate in the synthesis of leukotriene A4 methyl ester, is established via alumina-promoted rearrangement of ethyl (7Z)-3,4,7-tridecatrienoate to ethyl (2E,4Z,7Z)-2,4,7-tridecatrienoate as a key step.
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