Tetrahedron p. 5891 - 5898 (1997)
Update date:2022-08-17
Topics:
Cativiela, Carlos
Diaz-De-Villegas, Maria D.
Galvez, Jose A.
Lapena, Yolanda
A novel and efficient procedure for the synthesis of optically pure α-methylaspartic acid, based on the diastereoselective alkylation of (1S,2R,4R)-10-(dicyclohexylsulfamoyl)isobornyl 2-cyanopropanoate with α-halocarbonyl compounds, is described.
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