THE TRANSITION METAL-CATALYZED N-ALKYLATION AND N-HETEROCYCLIZATION. A REDUCTIVE TRANSFORMATION OF NITROBENZENE INTO N,N-DIALKYLANILINE AND 2,3-SUBSTITUTED QUINOLINE USING ALDEHYDE AND CARBON MONOXIDE

Article abstract of DOI:10.1246/cl.1980.429

The catalytic N-alkylation and N-heterocyclization of nitrobenzene occurs at 180 deg C under pressures of carbon monoxide (70 atm) in the presence of aldehyde and transition metal complexes to give 2,3-dialkyl quinoline and N,N-dialkylaniline in good yields.The product selectivity highly depends on the catalysts.