Facile synthesis of(e)-4-aryl-2-methyl-3-butenoic acids and their methyl esters by the condensation of tiglic acid dianion with arynes

Article abstract of DOI:10.1080/00397919608003700

The condensation of various arynes with tiglic acid dianion yields (E)-4-aryl-2-methyl-3-butenoic acids exclusively, after proton quench. These acids were characterized as their methyl esters, which were prepared by treating the acids with diazomethane.