Synthesis of cyclic imines via ethylenetetramethyldisilyl-protected ω-aminoimines. Application to the synthesis of alkaloids

Article abstract of DOI:10.1016/S0040-4039(00)60659-7

Cyclic imines, including several alkaloids such as myosmine, anabaseine and apoferrorosamine, were synthesized by α-alkylation of imines with ethylenetetramethyldisilyl-protected ω-bromoamines, followed by ring closure.