Synthesis of a new series of 2,8-disubstituted-2,8-diazaspiro[4,5]decan-1-ones as potential muscarinic agonists

DOI: 10.1016/0223-5234(94)90195-3

Source and publish data:

European Journal of Medicinal Chemistry p. 955 - 961 (1994)

Update date:2022-08-16

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Authors:

Cignarella

Villa Villa

Cattabeni

Reno Reno

Cimino Cimino

De Benedetti

Barlocco

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Article abstract of DOI:10.1016/0223-5234(94)90195-3

A new series of 2,8-disubstituted-2,8-diazaspiro[4,5]decan-1-ones 2 has been synthesized and tested for affinity towards muscarinic receptors by binding studies in comparison with the model RS-86. The membrane phosphatidylinositol turnover in the presence

Full text of DOI:10.1016/0223-5234(94)90195-3

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