UTILISATION DES ALCOXYTRIALKYLALUMINATES EN SYNTHESE ASYMETRIQUE: SYNTHESE DE L'ACIDE HYDROXY-2, METHYL-2 BUTANOIQUE ENANTIOMERIQUEMENT ENRICHI EN R OU S

Article abstract of DOI:10.1016/0022-328X(84)80167-9

The reaction of LiAlEt3OR^* with (-)-menthyl pyruvate (R^*OH = (-)-N-methylephedrine) and with (+)-menthyl pyruvate (R^*OH = (+)-N-methylephedrine) in hexane/ether as solvent produces the corresponding 2-hydroxy-2-methylbutan