
Journal of Organic Chemistry p. 4077 - 4085 (1980)
Update date:2022-08-03
Topics: Total synthesis Stereoselective Biogenetic precursor
Welch, Steven C.
Rao, A.S.C. Prakasa
Gibbs, Charles G.
Wong, Rayman Y.
Two approaches to the total synthesis of (+/-)-trichodiene (1) are reported from cis-fused lactone 10.Sequential alkylation of lactone 10 was observed to be highly stereoselective as established by the construction of diastereomeric lactone esters 12 and
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Doi:10.1081/NCN-100002424
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(2017)