
Tetrahedron Asymmetry p. 159 - 162 (1990)
Update date:2022-08-10
Topics:
Brunner, Henri
Muschiol, Manfred
Wischert, Thomas
Wiehl, Juergen
Commercial Ni powder, activated with H2 and modified with NaBr/(R,R)-(+)-rartaric acid are heterogeneous catalysts for the enantioselective hydrogenation of methyl acetoacetate (MAA) to give (R)-(-)-methyl 3-hydroxybutanoate (MHB) in up 76.9percent ee.
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