Synthesis of N-Protected Amino Esters via Palladium Catalysed Allylic Substitution

Article abstract of DOI:10.1016/0040-4039(93)88120-8

N-protected allylamines were prepared by palladium catalysed allylic substitution of the corresponding allyl acetates with a range of nitrogen nucleophiles.The so-formed N-protected allylamines were subjected to oxidative cleavage of the alkene to afford N-protected amino acids or esters.