Synthesis and pharmacological activity of benzo[b]thiophene-3-carboxylic acid derivatives

Article abstract of DOI:10.1002/jps.2600720228

Several dialkylaminoethyl benzo[b]thiophene-3-carboxylates, N-(2-dialkylaminoethyl)benzo[b]thiophene-3-carboxamides, 2-dialkylaminoethyl benzo[b]thiophene-3-carbamates, and substituted ureas with benzo[b]thiophene moiety, were prepared and tested for local anesthetic, anticholinergic, and antihistaminic activities. Several of the compoundds showed significant activity.