Tetrahedron Letters p. 5193 - 5196 (1999)
Update date:2022-08-17
Topics:
Dalla
Catteau
Pale
An intramolecular hydride delivery process largely contributes during the double reduction of α-keto esters into diols by NaBH4. In the case of enolic α-keto esters, the first step of the process, the reduction of the keto group, occurred exclusively through an 1,2-hydride addition despite the predominance of the tautomeric enolic form. The clear-cut difference of reaction rate between enolic and non enolic substrate 4 for reaction carried out in methanol is interpreted in terms of competitive hydride consumption due to the extremely favorable reaction between this solvent and NaBH4.
View MoreTianjin Hedong Red Cliff Chemical Reagent Factory
Contact:+86-022-84780548
Address:Li Ming Zhuang Gong Ye Yuan,Dongli District,Tianjin,China
Shijiazhuang Xinsheng Chemical Co., Ltd
Contact:+86-311-85965567
Address:Dongyang industry zone,xinle
Shanghai KFSL Pharmaceutical Technology Co.,Ltd.
Contact:+86-21-39971718
Address:859 jiadingchengliu shanghai
Yibin Hope Pharmaceutical Co., Ltd.
Contact:+86-831-5109851 86-831-5109836
Address:Luolong Industrial Zone,Nanxi, Yibin City, Sichuan, China. | Email: wishmarketing@gmail.com | Website: http://www.hopepharma.cc/
Contact:+86-574-87642758
Address:Room 901, Yinyi Bund Building, 132 Renmin Road
Doi:10.1111/cbdd.13164
(2018)Doi:10.1021/ja01165a011
(1950)Doi:10.1103/PhysRevB.59.1878
(1999)Doi:10.1016/j.tetlet.2005.02.040
(2005)Doi:10.1021/ja00711a069
(1970)Doi:10.1021/jo00105a050
(1994)