Halogen-Exchange Fluorination of Primary Alkyl Halides Using 1B Metal Fluorides-Pyridine Derivatives

Article abstract of DOI:10.1246/cl.1987.1675

Deep purplish red semicrystalline precipitates were obtained by the treatment of Cu2O with HF.After calcination at 100 deg C or higher temperature, this compound was successfully used as a highly effective halogen-exchange fluorination reagent for primary alkyl halides in the presence of pyridine derivatives.AgF and a mixture of CuF2 with copper powder also exhibited high activity in the reaction.