HALONIUM ION-INDUCED BIOSYNTHESIS OF CHLORINATED MARINE METABOLITES

Article abstract of DOI:10.1016/S0031-9422(00)80319-2

Bromoperoxidases do not directly oxidize the chloride ion; nevertheless, in the presence of bromide ions, chloride ions and hydrogen peroxide, bromoperoxidases react with alkenes and alkynes to produce bromochloro-derivatives.This same reaction is catalysed when seawater is the source of chloride and bromide ions.This suggests that bromonium ion-induced biosynthesis of chlorinated metabolites occurs in marine environments.The role of iodonium ions in the biosynthesis of chlorinated metabolites is also discussed.Key Word Index - Coralina sp.; Rhodophyta; biological halogenation; bromoperoxidase; enzymatic bromochlorination; marine chlorination; role of bromonium ions and iodonium ions; seawater.