Journal of Medicinal Chemistry p. 2739 - 2761 (2021)
Update date:2022-08-11
Topics:
Lawong, Aloysus
Gahalawat, Suraksha
Okombo, John
Striepen, Josefine
Yeo, Tomas
Mok, Sachel
Deni, Ioanna
Bridgford, Jessica L.
Niederstrasser, Hanspeter
Zhou, Anwu
Posner, Bruce
Wittlin, Sergio
Gamo, Francisco Javier
Crespo, Benigno
Churchyard, Alisje
Baum, Jake
Mittal, Nimisha
Winzeler, Elizabeth
Laleu, Beno?t
Palmer, Michael J.
Charman, Susan A.
Fidock, David A.
Ready, Joseph M.
Phillips, Margaret A.
Malaria control programs continue to be threatened by drug resistance. To identify new antimalarials, we conducted a phenotypic screen and identified a novel tetrazole-based series that shows fast-kill kinetics and a relatively low propensity to develop h
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