Cyanodibenzo[1,4]dioxines: A new family of synthons for substituted dibenzo[1,4]dioxines

Article abstract of DOI:10.1246/cl.1999.479

Cyanodibenzo[1,4]dioxines, previously unreported, are prepared quantitatively from catechols by nucleophilic fluorodisplacement from 2,3- and 3,4-difluorobenzonitriles, involving meta-fluorodisplacement, in DMF at 130 °C in the presence of potassium carbonate; the cyano-substituted dioxines can be transformed to other substituted dibenzo[1,4]dioxines.