Convenient synthesis of benzoylecgonine ethyl ester, a homolog of cocaine

Article abstract of DOI:10.1080/00397919208019293

Benzoylecgonine reacted with tetramethylethyhlenediamine to form a lipophilic ion pair, which was alkylated in the absence of water. The ethyl ester was readily recrystallized for pharmacological studies.

Full text of DOI:10.1080/00397919208019293

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Synthetic Communications: An
International Journal for Rapid
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Organic Chemistry
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Convenient Synthesis of
Benzoylecgonine Ethyl Ester, a
Homolog of Cocaine
a
a
Monica R. Brzezinski , Charles D. Christian
,
a
a
Meng-Feng Lin , Robert A. Dean , William F.
a
a
Bosron & Edwin T. Harper
a
Departments of Biochemistry and Molecular
Biology, Pathology and Medicine , Indiana University
School of Medicine , Indianapolis, IN, 46202-5122,
U.S.A.
Published online: 24 Sep 2006.
To cite this article: Monica R. Brzezinski , Charles D. Christian , Meng-Feng Lin ,
Robert A. Dean , William F. Bosron & Edwin T. Harper (1992) Convenient Synthesis of
Benzoylecgonine Ethyl Ester, a Homolog of Cocaine, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 22:7,
1027-1032, DOI: 10.1080/00397919208019293
To link to this article: http://dx.doi.org/10.1080/00397919208019293
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