Oxidative activity of organometallic compounds in relation to the coenzymes NADH and NADPH

Article abstract of DOI:10.1007/BF02252158

Kinetic investigations of the interaction of Hg and Sn-containing organometallic compounds with NADH and NADPH using spectra-photometric methods have shown that these compounds may act as oxidizing agents in relation to the coenzyme. Their oxidative activity depends on the nature and number of organic groups in the molecule. Comparison of the kinetic data for the activity of Hg and Sn compounds with those for Fe porphyrins imitating the active centers of redox enzymes indicates the competitiveness of the organometallic compounds and models of natural electron acceptors. 1999 KluwerAcademic/Plenum Publishers.