New processes for the synthesis of 2,6-dichloro-3- methylaniline-Ph-UL-14C and methyl 6-chloroanthranilate-Ph-UL-14C

Article abstract of DOI:10.1002/jlcr.2580341205

Two new processes were developed for the synthesis of 2,6-dichloro-3-methylaniline-Ph-UL-¹⁴C (1), a key intermediate in the synthesis of a DowElanco experimental product presently being considered for commercialization. Both processes afford product in much higher yields than that previously reported in the literature. One of the processes was subsequenly applied to the synthesis of methyl 6-chloroanthranilate-Ph-¹⁴C (12), used as an intermediate for a second potential product.