Catalytic enantioselective synthesis of (3S)-2,3-oxidosqualene

Article abstract of DOI:10.1016/S0040-4039(00)74200-6

An efficient and simple enantioselective process is described for the synthesis of (3S)-2,3-oxidosqualene (1) which provides this valuable compound contaminated with only 4% of the R enantiomer. The synthesis employs a chiral catalyst which is efficiently recovered for use.