Simple, stereocontrolled syntheses of 24(S),25-epoxy-22(R)- hydroxycholesterol, 22(R),24(S)-dihydroxycholesterol and diastereomers, new ligands for binding and activation of LXRs

DOI: 10.1016/S0040-4039(98)02182-0

Source and publish data:

Tetrahedron Letters p. 9355 - 9356 (1998)

Update date:2022-08-28

Topics:

Authors:

Corey Corey

Grogan, Michael J.

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Article abstract of DOI:10.1016/S0040-4039(98)02182-0

Described herein are stereocontrolled syntheses of a series of sidechain oxygenated cholesterols for the study of binding and activation of nuclear receptors of the LXR family.

Full text of DOI:10.1016/S0040-4039(98)02182-0

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