Journal of the Chemical Society. Perkin transactions I p. 355 - 358 (1996)
Update date:2022-08-11
Topics:
Shimoda, Kei
Ito, Diana I.
Izumi, Shunsuke
Hirata, Toshifumi
A reductase isolated from cultured cells of Nicotiana tabacum has been characterized and used in the reduction of a C=C bond adjacent to a carbonyl group. The stereochemistry of the latter reaction has been investigated by 2H NMR and mass spectroscopy. It was found that the reductase reduces stereospecifically the C=C bond of verbenone and carvone by syn addition of hydrogen from the re face at the β-position and the re face at the α-position to the carbonyl group; the hydrogen atoms participating in the enzymatic reduction at the α- and β-positions originate from the medium (H2O) and the pro-4S hydrogen of NADPH, respectively.
View MoreContact:+86-13666670345
Address:Agricultural Development Zone, Haining, Jiaxing, Zhejiang
Contact:+86-21-38122007
Address:2, Lane 1123, Kangqiao Road, Pudong New Area, Shanghai
Jiangxi Huashi Pharmaceutical Co., Ltd
Contact:+86-795-4509628
Address:No.199, Ningbo Avenue, Fengxin industrial park, Fengxin county, Yichun city, Jiangxi
Contact:+86-371-86058576
Address:NO.32, Jingsan Road, Zhengzhou, China
website:http://www.china-sinoway.com
Contact:+86-592-5853819
Address:16/F,Huicheng Comm,Complex,No839 XiaHe Rd, Xiamen,China
Doi:10.1016/j.tetlet.2009.11.052
(2010)Doi:10.1039/c2jm35031a
(2012)Doi:10.1021/ja02230a006
(1919)Doi:10.1021/ja052935r
(2005)Doi:10.1002/ejoc.201500811
(2015)Doi:10.1063/1.459950
(1991)
