Chemoenzymatic synthesis of 1,3-dideoxynojirimycin

DOI: 10.1016/S0040-4039(00)73172-8

Source and publish data:

Tetrahedron Letters p. 1833 - 1834 (1994)

Update date:2022-08-31

Topics:

Authors:

Johnson, Carl R.

Golebiowski, Adam

Braun, Matthew P.

Sundram, Hari

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Article abstract of DOI:10.1016/S0040-4039(00)73172-8

Enone 3, readily available from cyclopentadiene, was transformed via Pd(0)-mediated carbon monoxide coupling, ozonolysis and reductive amination to enantiopure 1,3-dideoxynojirimycin (7) in high diastereoselectivity.

Full text of DOI:10.1016/S0040-4039(00)73172-8

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