A New Method for Introducing Some Active Methylene or Methine Groups to the 3-Position of Pyrrolidine or Piperidine Skeleton, and Its Application to Preparation of a Key Intermydiate for (+/-)-Eburnamonine Synthesis

DOI: 10.1246/cl.1987.1447

Source and publish data:

Chemistry Letters p. 1447 - 1450 (1987)

Update date:2022-08-25

Topics:

Authors:

Shono, Tatsuya

Matsumura, Yoshihiro

Ogaki, Masaru

Onomura, Osamu

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1987.1447

A new method for introducing a bis(methoxycarbonyl)methyl or 2-oxopropyl group to the 3-position of pyrrolidine or piperidine skeleton has been exploited, and this method could be used in the synthesis of a key intermediate for the (+/-)-eburnamonine synthesis.

Full text of DOI:10.1246/cl.1987.1447

Products guided by the article

Product name:1(2H)-Pyridinecarboxylicacid,3,4-dihydro-,methylester(9CI)

Cas No:56475-87-7

R&D Labs maybe for 56475-87-7

Chengdu Cogon Bio-tech Co., Ltd.

Contact:86-28-85171192

Address:NO.52.YongFeng Rd. Chengdu,610041,P.R.China.
suzhou chukai pharmateach co,.ltd

Contact:86-512-88812511

Address:Building 3, Wujiang Scientific Innovation Park, 2358 Changan Rd, Wujiang 215200, Jiangsu Province, P. R. China
Shijiazhuang Haotian Chemical Co., Ltd.

Contact:86-311-85044374

Address:293 Donggang Road
ZiBO KuoDing Trade company Ltd

website:http://www.sdzbkd.com

Contact:86-13361591822

Address:GongQingTuan road
Zhaodu Fine Chemical Plant

Contact:86-310-8067016

Address:East Fuhua Road,Tiexi Chemical Industrial Estate,Hebei,China

Relevant to this article

Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point

Doi:10.1021/acs.jmedchem.7b00267
(2017)
Doi:10.1039/jr9390000420
(1939)
Synthesis of α,α-Disulfenylated Aldehydes via Oxidative Transformation of Tertiary Amines

Doi:10.1021/acs.orglett.5b02876
(2015)
Synthesis, structural characterization and catalytic transfer hydrogenation of ruthenium(II) carbonyl complexes bearing N,N,O pincer type benzoylhydrazone ligands

Doi:10.1016/j.poly.2014.12.016
(2015)
Synthesis and stability of [1,3-¹⁴C₂]-glyceryl trinitrate

Doi:10.1002/jlcr.2580341115
(1994)
Direct conversion of alcohols to α-chloro aldehydes and α-chloro ketones

Doi:10.1021/ol5024568
(2014)

Article Doi