1844
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4
3
2.
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Scheme 6.
4. Shuttleworth, S. J.; Allin, S. M.; Sharma, P. K. Synthesis
1
5
Recycling; De Vos, D. E., Vankelecom, I. F. J., Jacobs, P.,
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997, 11, 1217.
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Scheme 7.
Rev. 2000, 100, 2159.
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8
´
8
9
1
1
2
1
11.
that obtained in the homogeneous system using (RuCl2–
BINAP), in methanol (100% ee and conversion).
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1. Kumobayashi, H. Recl. Trav. Chim. Pays-Bas 1996, 115,
01.
We have shown that polymer-supported ligands such as
amino alcohol resins and polymers derived from
BINAP were able to reduce C¼C or C¼O bonds in
biphasic catalytic conditions. Moreover, the hetero-
geneization of BINAP into polyurea was successful and
allowed the efficient asymmetric hydrogenation of car-
bonyl compounds.
2. Bayston, D. J.; Fraser, J. L.; Ashton, M. R.; Baxter, A. D.;
Polywka, M. E. C.; Moses, E. J. Org. Chem. 1998, 63, 3137.
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1
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1
From the synthetic point of view, in most cases, the use
of these Ru-based ligands led to high conversions and in
some cases good enantioselectivities. On the other hand,
they offer easy separation of the catalyst from the reac-
tion mixture and their reuse is, in some cases, effective
without any loss either of conversion or enantio-
selectivity.
1
1
H. J. Chem. Soc., Chem. Commun. 1989, 5, 1208.
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2
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References and Notes
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