Tetrahedron Letters p. 957 - 960 (1998)
Update date:2022-08-30
Topics:
Robustell, Brian
Ikuro, Abe
Prestwich, Glenn D.
A convergent asymmetric synthesis provided (3S)11-fluoro-2,3- oxidosqualene (11-FOS, 14), which was cyclized by bacterial squalene:hopane cyclase to a bridged ether. 11-FOS was neither a substrate nor an inhibitor for vertebrate oxidosqualene:lanosterol c
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